2017

Journal Articles

50.

Volohonsky, Gloria; Hopp, Ann-Katrin; Saenger, Mélanie; Soichot, Julien; Scholze, Heidi; Boch, Jens; Blandin, Stéphanie A; Marois, Eric

Transgenic Expression of the Anti-parasitic Factor TEP1 in the Malaria Mosquito Anopheles gambiae Journal Article

PLOS Pathogens, 13 (1), pp. e1006113, 2017, ISSN: 1553-7374.

Links | BibTeX | Tags: Anopheles gambiae, anti-parasitic factor, Malaria, TEP1, Transgenic

49.

Mussabekova, Assel; Daeffler, Laurent; Imler, Jean-Luc

Innate and intrinsic antiviral immunity in Drosophila Journal Article

Cell. Mol. Life Sci., 2017, ISSN: 1420-9071.

Abstract | Links | BibTeX | Tags: Argonaute 2, Dicer-2, IMD pathway, Jak/STAT pathway, NF-κB

2016

Journal Articles

48.

Lee, Kwang-Zin; Lestradet, Matthieu; Socha, Catherine; Schirmeier, Stefanie; Schmitz, Antonin; Spenlé, Caroline; Lefebvre, Olivier; Keime, Céline; Yamba, Wennida M.; Bou Aoun, Richard; Liegeois, Samuel; Schwab, Yannick; Simon-Assmann, Patricia; Dalle, Frédéric; Ferrandon, Dominique

Enterocyte Purge and Rapid Recovery Is a Resilience Reaction of the Gut Epithelium to Pore-Forming Toxin Attack Journal Article

Cell Host & Microbe, 2016, ISSN: 1931-3128.

Abstract | Links | BibTeX | Tags: Epithelium, gut, resilience

47.

Ehrhardt, Katharina; Deregnaucourt, Christiane; Goetz, Alice-Anne; Tzanova, Tzvetomira; Gallo, Valentina; Arese, Paolo; Pradines, Bruno; Adjalley, Sophie H; Bagrel, Denyse; Blandin, Stephanie; Lanzer, Michael; Davioud-Charvet, Elisabeth

The redox-cycler plasmodione is a fast acting antimalarial lead compound with pronounced activity against sexual and early asexual blood-stage parasites Journal Article

Antimicrob. Agents Chemother., 60 (9), pp. 5146-5158 , 2016, ISSN: 1098-6596.

Abstract | Links | BibTeX | Tags: antimalarial, parasites, Plasmodium, redox-cycler

46.

Lamiable, Olivier; Kellenberger, Christine; Kemp, Cordula; Troxler, Laurent; Pelte, Nadège; Boutros, Michael; Marques, Joao Trindade; Daeffler, Laurent; Hoffmann, Jules A; Roussel, Alain; Imler, Jean-Luc

Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila Journal Article

PNAS, 113 (3), pp. 698–703, 2016, ISSN: 0027-8424, 1091-6490.

Abstract | Links | BibTeX | Tags: antiviral immunity, bioinformatic, cytokine, Edin, Sindbis Virus, virokine

45.

Lamiable, Olivier; Arnold, Johan; da de Faria, Isaque Joao Silva; Olmo, Roenick Proveti; Bergami, Francesco; Meignin, Carine; Hoffmann, Jules A; Marques, Joao Trindade; Imler, Jean-Luc

Analysis of the Contribution of Hemocytes and Autophagy to Drosophila Antiviral Immunity Journal Article

J. Virol., 90 (11), pp. 5415–5426, 2016, ISSN: 0022-538X, 1098-5514.

Links | BibTeX | Tags: antiviral immunity, Autophagy, Hemocytes

44.

Marques, João T; Imler, Jean-Luc

The diversity of insect antiviral immunity: insights from viruses Journal Article

Current Opinion in Microbiology, 32 , pp. 71–76, 2016, ISSN: 1369-5274.

Abstract | Links | BibTeX | Tags:

43.

Martins, Nelson; Imler, Jean-Luc; Meignin, Carine

Discovery of novel targets for antivirals: learning from flies Journal Article

Curr Opin Virol, 20 , pp. 64–70, 2016, ISSN: 1879-6265.

Abstract | Links | BibTeX | Tags: antiviral, target

42.

Lamiable, Olivier; Meignin, Carine; Imler, Jean-Luc

WntD and Diedel: Two immunomodulatory cytokines in Drosophila immunity Journal Article

Fly (Austin), 10 (4), pp. 187–194, 2016, ISSN: 1933-6942.

Abstract | Links | BibTeX | Tags: Cytokines, Drosophila, IMD pathway, innate immunity, virus

Book Chapters

41.

Paro, Simona; Imler, Jean-Luc

Encyclopedia of Immunobiology Book Chapter

Ratcliffe, M (Ed.): 1 , Chapter “Immunity in insects”, pp. 454-461, Elsevier, 2016.

BibTeX | Tags: Immunity, Insect

2015

Journal Articles

40.

Veillard, Florian; Troxler, Laurent; Reichhart, Jean-Marc

Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation Journal Article

Biochimie, 122 , pp. 255-269, 2015, ISBN: 0300-9084.

Abstract | Links | BibTeX | Tags: bioinformatic, Chymotrypsin, clip domain, Immunity, Insect, Melanization, Serine Proteases, Serpin, Toll

39.

Pompon, Julien; Levashina, Elena A

A New Role of the Mosquito Complement-like Cascade in Male Fertility in Anopheles gambiae Journal Article

PLoS Biology, 13 (9), pp. e1002255, 2015.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, TEP1

38.

Chamy, Laure El; Matt, Nicolas; Ntwasa, Monde; Reichhart, Jean-Marc

The multilayered innate immune defense of the gut Journal Article

Biomed J, 38 (4), pp. 276–284, 2015, ISSN: 2320-2890.

Abstract | Links | BibTeX | Tags: fly, gut, innate immunity

37.

Aguiar, Eric Roberto Guimarães Rocha; Olmo, Roenick Proveti; Paro, Simona; Ferreira, Flavia Viana; da de Faria, Isaque João Silva; Todjro, Yaovi Mathias Honore; Lobo, Francisco Pereira; Kroon, Erna Geessien; Meignin, Carine; Gatherer, Derek; Imler, Jean-Luc; Marques, João Trindade

Sequence-independent characterization of viruses based on the pattern of viral small RNAs produced by the host Journal Article

Nucleic Acids Research, 43 (13), pp. 6191–6206, 2015, ISSN: 1362-4962.

Abstract | Links | BibTeX | Tags: Contig Mapping, Female, Insects, Ovary, Plants, RNA, Sequence Analysis, Small Untranslated, Vertebrates, Viral, Viral Tropism, Viruses

36.

Volohonsky, Gloria; Terenzi, Olivier; Soichot, Julien; Naujoks, Daniel A; Nolan, Tony; Windbichler, Nikolai; Kapps, Delphine; Smidler, Andie L; Vittu, Anaïs; Costa, Giulia; Steinert, Stefanie; Levashina, Elena A; Blandin, Stéphanie A; Marois, Eric

Tools for Anopheles gambiae Transgenesis Journal Article

G3 (Bethesda), 5 (6), pp. 1151-63, 2015.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, bioinformatic, transgenesis

35.

Paro, Simona; Imler, Jean-Luc; Meignin, Carine

Sensing viral RNAs by Dicer/RIG-I like ATPases across species Journal Article

Current Opinion in Immunology, 32 , pp. 106–113, 2015, ISSN: 1879-0372.

Abstract | Links | BibTeX | Tags: Adenosine Triphosphatases, DEAD-box RNA Helicases, Humans, Protein Binding, Protein Interaction Domains and Motifs, Ribonuclease III, RNA, Viral, Virus Diseases, Viruses

34.

Neafsey, D E; Waterhouse, R M; Abai, M R; Aganezov, S S; Alekseyev, M A; Allen, J E; Amon, J; Arcà, B; Arensburger, P; Artemov, G; Assour, L A; Basseri, H; Berlin, A; Birren, B W; Blandin, Stéphanie A; Brockman, A I; Burkot, T R; Burt, A; Chan, C S; Chauve, C; Chiu, J C; Christensen, M; Costantini, C; Davidson, V L M; Deligianni, E; Dottorini, T; Dritsou, V; Gabriel, S B; Guelbeogo, W M; Hall, A B; Han, M W; Hlaing, T; Hughes, D S T; Jenkins, A M; Jiang, X; Jungreis, I; Kakani, E G; Kamali, M; Kemppainen, P; Kennedy, R C; Kirmitzoglou, I K; Koekemoer, L L; Laban, N; Langridge, N; Lawniczak, M K N; Lirakis, M; Lobo, N F; Lowy, E; MacCallum, R M; Mao, C; Maslen, G; Mbogo, C; McCarthy, J; Michel, K; Mitchell, S N; Moore, W; Murphy, K A; Naumenko, A N; Nolan, Tony; Novoa, E M; O’Loughlin, S; Oringanje, C; Oshaghi, M A; Pakpour, N; Papathanos, P A; Peery, A N; Povelones, Michael; Prakash, A; Price, D A; Rajaraman, A; Reimer, L J; Rinker, D C; Rokas, A; Russell, T L; Sagnon, N F; Sharakhova, M V; Shea, T; Simão, F A; Simard, F; Slotman, M A; Somboon, P; Stegniy, V; Struchiner, C J; Thomas, G W C; Tojo, M; Topalis, P; Tubio, J M C; Unger, M F; Vontas, J; Walton, C; Wilding, C S; Willis, J H; Wu, Y-C; Yan, G; Zdobnov, E M; Zhou, X; Catteruccia, Flaminia; Christophides, Georges K; Collins, F H; Cornman, R S; Crisanti, Andrea; Donnelly, M J; Emrich, S J; Fontaine, M C; Gelbart, W; Hahn, M W; Hansen, I A; Howell, P I; Kafatos, Fotis C; Kellis, M; Lawson, D; Louis, C; Luckhart, S; Muskavitch, M A T; Ribeiro, J M; Riehle, M A; Sharakhov, I V; Tu, Z; Zwiebel, L J; Besansky, N J

Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes. Journal Article

Science, 347 (6217), pp. 1258522, 2015.

Abstract | Links | BibTeX | Tags: Anopheles, genomes

33.

Girardi, Erika; Lefèvre, Mathieu; Chane-Woon-Ming, Béatrice; Paro, Simona; Claydon, Bill; Imler, Jean-Luc; Meignin, Carine; Pfeffer, Sébastien

Cross-species comparative analysis of Dicer proteins during Sindbis virus infection Journal Article

Scientific Reports, 5 , pp. 10693, 2015, ISSN: 2045-2322.

Abstract | Links | BibTeX | Tags:

32.

Brunke, Sascha; Quintin, Jessica; Kasper, Lydia; Jacobsen, Ilse D; Richter, Martin E; Hiller, Ekkehard; Schwarzmüller, Tobias; d'Enfert, Christophe; Kuchler, Karl; Rupp, Steffen; Hube, Bernhard; Ferrandon, Dominique

Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts Journal Article

Dis Model Mech, 8 (5), pp. 473–486, 2015, ISSN: 1754-8411.

Abstract | Links | BibTeX | Tags: Alternative infection models, Candida glabrata, Fungal virulence factors, Mutant library, Signature-tagged mutagenesis

31.

Hafirassou, Lamine Mohamed; Meignin, Carine; Baumert, Thomas; Schuster, Catherine

[From fly to man: RACK1, an essential actor of the dependent viral translation of IRES]. Journal Article

Médecine sciences : M/S, 31 (5), pp. 469–472, 2015.

BibTeX | Tags:

30.

Hammond, Andrew; Galizi, Roberto; Kyrou, Kyros; Simoni, Alekos; Siniscalchi, Carla; Katsanos, Dimitris; Gribble, Matthew; Baker, Dean; Marois, Eric; Russell, Steven; Burt, Austin; Windbichler, Nikolai; Crisanti, Andrea; Nolan, Tony

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae Journal Article

Nature Biotechnology, 34 (1), pp. 78–83, 2015, ISSN: 1087-0156, 1546-1696.

Links | BibTeX | Tags:

Book Chapters

29.

Majzoub, Karim; Imler, Jean-Luc

Encyclopedia of Molecular Cell Biology and Molecular Medicine Book Chapter

Verlag, Wiley-VCH (Ed.): 1 , Chapter « RNAi to treat virus infections », pp. 192-228, GmbH & Co. KGaA, 2015.

Abstract | Links | BibTeX | Tags: antiviral, argonaute, delivery, Immunity, lipofection, microRNA (miRNA), RNA Virus Infections, RNAi, small hairpin RNA (shRNA), small interfering RNA (siRNA)

2014

Journal Articles

28.

Chtarbanova, Stanislava; Lamiable, Olivier; Lee, Kwang-Zin; Galiana, Delphine; Troxler, Laurent; Meignin, Carine; Hetru, Charles; Hoffmann, Jules A; Daeffler, Laurent; Imler, Jean-Luc

Drosophila C virus systemic infection leads to intestinal obstruction Journal Article

Journal of Virology, 88 (24), pp. 14057–14069, 2014, ISSN: 1098-5514.

Abstract | Links | BibTeX | Tags: bioinformatic, Dicistroviridae, Female, Gastrointestinal Tract, Gene Expression Profiling, Intestinal Obstruction, Muscle, Nodaviridae, Sindbis Virus, Smooth, Viral Tropism

27.

Majzoub, Karim; Hafirassou, Mohamed Lamine ; Meignin, Carine ; Goto, Akira ; Marzi, Stefano ; Fedorova, Antonina ; Verdier, Yann ; Vinh, Joëlle ; Hoffmann, Jules A; Martin, Franck ; Baumert, Thomas F; Schuster, Catherine ; Imler, Jean-Luc

RACK1 controls IRES-mediated translation of viruses Journal Article

Cell, 159 (5), pp. 1086–1095, 2014, ISSN: 1097-4172.

Abstract | Links | BibTeX | Tags: Cell Line, Cell Surface, Cytoplasmic and Nuclear, Dicistroviridae, GTP-Binding Proteins, Hepacivirus, Hepatocytes, Humans, Insect Viruses, Models, Molecular, Neoplasm Proteins, Peptide Initiation Factors, Protein Biosynthesis, Receptors, Regulatory Sequences, Ribonucleic Acid, Tumor, Virus Replication

26.

Bonnay, François; Nguyen, Xuan-Hung; Cohen-Berros, Eva; Troxler, Laurent; Batsche, Eric; Camonis, Jacques; Takeuchi, Osamu; Reichhart, Jean-Marc; Matt, Nicolas

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling Journal Article

EMBO J., 33 (20), pp. 2349–2362, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: bioinformatic, Cell Cycle Proteins, Chromatin Assembly and Disassembly, chromatin remodeling, DNA-Binding Proteins, Female, Genetic, Immunity, Innate, Innate immune response, Male, Mutation, NF-kappa B, NF‐κB, Promoter Regions, Proteomics, Trans-Activators, Transcription Factors, Transcriptional Activation, Two-Hybrid System Techniques

25.

Tartey, Sarang; Matsushita, Kazufumi ; Vandenbon, Alexis ; Ori, Daisuke ; Imamura, Tomoko ; Mino, Takashi ; Standley, Daron M; Hoffmann, Jules A; Reichhart, Jean-Marc ; Akira, Shizuo ; Takeuchi, Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Journal Article

EMBO J., 33 (20), pp. 2332–2348, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

24.

Amcheslavsky, Alla; Song, Wei; Li, Qi; Nie, Yingchao; Bragatto, Ivan; Ferrandon, Dominique; Perrimon, Norbert; Ip, Tony Y

Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila Journal Article

Cell Rep, 9 (1), pp. 32–39, 2014, ISSN: 2211-1247.

Abstract | Links | BibTeX | Tags: Cell Differentiation, Enterocytes, Enteroendocrine Cells, Female, Homeostasis, Intestines, Male, Stem Cells, Tachykinins

23.

Lamiable, Olivier; Imler, Jean-Luc

Induced antiviral innate immunity in Drosophila Journal Article

Current Opinion in Microbiology, 20 , pp. 62–68, 2014, ISSN: 1879-0364.

Abstract | Links | BibTeX | Tags: Gene Expression Regulation, Host-Pathogen Interactions, Immunity, Innate, RNA Viruses, Signal Transduction

22.

Goto, Akira; Fukuyama, Hidehiro ; Imler, Jean-Luc ; Hoffmann, Jules A

The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response Journal Article

The Journal of Biological Chemistry, 289 (30), pp. 20470–20476, 2014, ISSN: 1083-351X.

Abstract | Links | BibTeX | Tags: Cell Line, Chromatin Assembly and Disassembly, Epistasis, Escherichia coli, Escherichia coli Infections, Genetic, Immunity, Innate, NF-kappa B, Repressor Proteins, Signal Transduction, Transcription Factors

21.

Baldini, Francesco; Segata, N; Pompon, Julien; Marcenac, P; Shaw, W R; Dabire, R; Diabate, A; Levashina, Elena A; Catteruccia, Flaminia

Evidence of natural Wolbachia infections in field populations of Anopheles gambiae Journal Article

Nature Commun., 5 , pp. 3985, 2014.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, field, Wolbachia

20.

Bernardini, F; Galizi, R; Menichelli, M; Papathanos, P A; Dritsou, V; Marois, Eric; Crisanti, Andrea; Windbichler, Nikolai

Site-specific genetic engineering of the Anopheles gambiae Y chromosome Journal Article

Proc Natl Acad Sci U S A., 111 (21), pp. 7600-5, 2014.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, biotechnology, SIT, transgenesis

19.

Imler, Jean-Luc

Overview of Drosophila immunity: a historical perspective Journal Article

Developmental and Comparative Immunology, 42 (1), pp. 3–15, 2014, ISSN: 1879-0089.

Abstract | Links | BibTeX | Tags: Allergy and Immunology, Animal, Antimicrobial Cationic Peptides, Antimicrobial peptides, History, Humans, IMD pathway, Immunity, Innate, innate immunity, Models, Pattern recognition receptors, Signal Transduction, Toll-Like Receptors

18.

Leclerc, Vincent; Chamy, Laure El; Ntwasa, Monde; Reichhart, Jean-Marc

Drosophila melanogaster model in innate immunity. Journal Article

Trends in Entomology, 10 , pp. 73–86, 2014.

Abstract | BibTeX | Tags:

17.

Haller, Samantha; Limmer, Stefanie; Ferrandon, Dominique

Assessing Pseudomonas virulence with a nonmammalian host: Drosophila melanogaster Journal Article

Methods Mol. Biol., 1149 , pp. 723–740, 2014, ISSN: 1940-6029.

Abstract | Links | BibTeX | Tags: Animal, Antimicrobial Cationic Peptides, Biological Assay, Colony Count, Disease Models, Hemolymph, Host-Pathogen Interactions, Mammals, Microbial, Pseudomonas aeruginosa, Pseudomonas Infections, Reverse Transcriptase Polymerase Chain Reaction, Virulence

16.

Lestradet, Matthieu; Lee, Kwan Zin; Ferrandon, Dominique

Drosophila as a model for intestinal infections Journal Article

Methods Mol Biol, 1197 , pp. 11–40, 2014, ISSN: 1940-6029 (Electronic) 1064-3745 (Linking).

Abstract | Links | BibTeX | Tags: Animal, Bacterial Physiological Phenomena, Disease Models, Gastrointestinal Tract, Host-Pathogen Interactions

15.

Schwarzmüller, Tobias; Ma, Biao; Hiller, Ekkehard; Istel, Fabian; Tscherner, Michael; Brunke, Sascha; Ames, Lauren; Firon, Arnaud; Green, Brian; Cabral, Vitor; Marcet-Houben, Marina; Jacobsen, Ilse D; Quintin, Jessica; Seider, Katja; Frohner, Ingrid; Glaser, Walter; Jungwirth, Helmut; Bachellier-Bassi, Sophie; Chauvel, Murielle; Zeidler, Ute; Ferrandon, Dominique; Gabaldón, Toni; Hube, Bernhard; d'Enfert, Christophe; Rupp, Steffen; Cormack, Brendan; Haynes, Ken; Kuchler, Karl

Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes Journal Article

PLoS Pathog., 10 (6), pp. e1004211, 2014, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Antifungal Agents, Azoles, Biofilms, Candida glabrata, Candidiasis, Cell Wall, Drug Resistance, Echinocandins, Fungal, Fungal Proteins, Gene Deletion, Gene Knockout Techniques, Gene Library, Microbial Sensitivity Tests, Osmotic Pressure, Phenotype

Book Chapters

14.

Gabrieli, P; Marois, Eric; Catteruccia, Flaminia

Transgenic insects: techniques and applications Book Chapter

Benedicts, MQ (Ed.): Chapter Sexual sterilization of mosquitoes, pp. 188-207, CABI, 2014.

BibTeX | Tags: Insects, sterile

13.

Imler, Jean-Luc; Hoffmann, Jules A

Le défi des maladies infectieuses Book Chapter

Ph. Cramer collection Guérir et prévenir demain, (Ed.): Chapter « L’immunité innée », pp. 167-174, Editions DOCIS, 2014, ISBN: 978-2-85525-390-9.

Abstract | BibTeX | Tags: innate immunity, maladies infectieuses

2013

Journal Articles

12.

Petrillo, Jessica E; Venter, Arno P; Short, James R; Gopal, Radhika ; Deddouche, Safia ; Lamiable, Olivier ; Imler, Jean-Luc ; Schneemann, Anette

Cytoplasmic granule formation and translational inhibition of nodaviral RNAs in the absence of the double-stranded RNA binding protein B2 Journal Article

Journal of Virology, 87 (24), pp. 13409–13421, 2013, ISSN: 1098-5514.

Abstract | Links | BibTeX | Tags: Capsid Proteins, Cell Line, Cricetinae, Cytoplasmic Granules, Double-Stranded, Nodaviridae, Protein Biosynthesis, RNA, RNA Virus Infections, RNA-Binding Proteins, Viral, Viral Proteins

11.

Smidler, Andie L; Terenzi, Olivier; Soichot, Julien; Levashina, Elena A; Marois, Eric

Targeted Mutagenesis in the Malaria Mosquito Using TALE Nucleases Journal Article

PLoS One, 8 (8), pp. e74511, 2013.

Abstract | Links | BibTeX | Tags: Mutagenesis, TALEN

10.

Lamacchia, Marina; Clayton, John Randy; Wang-Sattler, R; Steinmetz, Lars M; Levashina, Elena A; Blandin, Stéphanie A

Silencing of Genes and Alleles by RNAi in Anopheles gambiae Journal Article

Methods Mol Biol., 923 , pp. 161-76, 2013.

Abstract | BibTeX | Tags: dsRNA, RNAi

9.

Fukuyama, Hidehiro; Verdier, Yann; Guan, Yongsheng; Makino-Okamura, Chieko; Shilova, Victoria; Liu, Xi; Maksoud, Elie; Matsubayashi, Jun; Haddad, Iman; Spirohn, Kerstin; Ono, Kenichiro; Hetru, Charles; Rossier, Jean; Ideker, Trey; Boutros, Michael; Vinh, Joëlle; Hoffmann, Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Journal Article

Proc. Natl. Acad. Sci. U.S.A., 110 (26), pp. 10717–10722, 2013, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Amino Acid, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, Host-Pathogen Interactions, Humans, IMD interactome, Insect, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier

8.

Nsango, Sandrine E; Pompon, Julien; Xie, Ting; Rademacher, Annika; Fraiture, Malou; Thoma, Martine; Awono-Ambene, P H; Moyou, R S; Morlais, Isabelle; Levashina, Elena A

AP-1/Fos-TGase2 axis mediates wounding-induced Plasmodium falciparum killing in Anopheles gambiae Journal Article

J Biol Chem., 288 (22), pp. 16145-54, 2013.

Abstract | Links | BibTeX | Tags: AP-1, Fos-TGase2, wounding

7.

Kobayashi, Taira; Ogawa, Michinaga; Sanada, Takahito; Mimuro, Hitomi; Kim, Minsoo; Ashida, Hiroshi; Akakura, Reiko; Yoshida, Mitsutaka; Kawalec, Magdalena; Reichhart, Jean-Marc; Mizushima, Tsunehiro; Sasakawa, Chihiro

The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection Journal Article

Cell Host Microbe, 13 (5), pp. 570–583, 2013, ISSN: 1934-6069.

Abstract | Links | BibTeX | Tags: Animal, Bacillary, Bacterial, Bacterial Proteins, Caspases, Cell Death, Cell Line, Disease Models, DNA, Dysentery, Enzyme Inhibitors, Epithelial Cells, Escherichia coli, Gene Knockout Techniques, Guinea Pigs, Host-Pathogen Interactions, Humans, Initiator, Protein Binding, Protein Interaction Mapping, Salmonella typhimurium, Sequence Analysis, Shigella flexneri, Virulence Factors

6.

Quintin, Jessica; Asmar, Joelle; Matskevich, Alexey A; Lafarge, Marie-Céline; Ferrandon, Dominique

The Drosophila Toll pathway controls but does not clear Candida glabrata infections Journal Article

J. Immunol., 190 (6), pp. 2818–2827, 2013, ISSN: 1550-6606.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Animal, Antigens, Candida glabrata, Candidiasis, Cells, Cultured, Differentiation, Disease Models, Immunologic, Phagocytosis, Receptors, Signal Transducing, Signal Transduction, Toll-Like Receptors, Virulence

5.

Bonnay, François; Cohen-Berros, Eva ; Hoffmann, Martine ; Kim, Sabrina Y; Boulianne, Gabrielle L; Hoffmann, Jules A; Matt, Nicolas ; Reichhart, Jean-Marc

Big bang gene modulates gut immune tolerance in Drosophila Journal Article

Proc. Natl. Acad. Sci. U.S.A., 110 (8), pp. 2957–2962, 2013, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Immune Tolerance, Longevity, Membrane Proteins

4.

Ferrandon, Dominique

The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience Journal Article

Curr. Opin. Immunol., 25 (1), pp. 59–70, 2013, ISSN: 1879-0372.

Abstract | Links | BibTeX | Tags: Adult Stem Cells, Aging, Animal, Cell Proliferation, Disease Models, Enterocytes, Humans, Immunity, Intestinal Mucosa, Metagenome, Stem Cell Niche, Wound Healing

3.

Kemp, Cordula; Mueller, Stefanie ; Goto, Akira ; Barbier, Vincent ; Paro, Simona ; Bonnay, François ; Dostert, Catherine ; Troxler, Laurent ; Hetru, Charles ; Meignin, Carine ; Pfeffer, Sébastien ; Hoffmann, Jules A; Imler, Jean-Luc

Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila Journal Article

Journal of Immunology (Baltimore, Md.: 1950), 190 (2), pp. 650–658, 2013, ISSN: 1550-6606.

Abstract | Links | BibTeX | Tags: Alphavirus, Alphavirus Infections, bioinformatic, DNA Virus Infections, Gene Expression Regulation, Genetically Modified, Janus Kinases, Male, Nodaviridae, Ribonuclease III, RNA Helicases, RNA Interference, RNA Virus Infections, Transcription Factors

2.

Baron, Olga Lucia; van West, Pieter; Industri, Benoit; Ponchet, Michel; Dubreuil, Géraldine; Gourbal, Benjamin; Reichhart, Jean-Marc; Coustau, Christine

Parental transfer of the antimicrobial protein LBP/BPI protects Biomphalaria glabrata eggs against oomycete infections Journal Article

PLoS Pathog., 9 (12), pp. e1003792, 2013, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Acute-Phase Proteins, Antimicrobial Cationic Peptides, Biomphalaria, Blood Proteins, Carrier Proteins, Cell Membrane, Cell Membrane Permeability, Cloning, Escherichia coli, Female, Immunity, Infection, Maternally-Acquired, Membrane Glycoproteins, Microbial Sensitivity Tests, Molecular, Oomycetes, Recombinant Proteins, Zygote

1.

Ayyaz, Arshad; Giammarinaro, Philippe; Liégeois, Samuel; Lestradet, Matthieu; Ferrandon, Dominique

A negative role for MyD88 in the resistance to starvation as revealed in an intestinal infection of Drosophila melanogaster with the Gram-positive bacterium Staphylococcus xylosus Journal Article

Immunobiology, 218 (4), pp. 635–644, 2013, ISSN: 1878-3279.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Animal, Antigens, Differentiation, Disease Models, Immunity, Immunologic, Innate, Intestinal Diseases, Mucosal, Mutation, Receptors, Signal Transducing, Staphylococcal Infections, Staphylococcus, Starvation, Toll-Like Receptors