Group leader: Dominique FERRANDON
Deciphering the molecular pathways involved in host-pathogen interactions

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We aim to decipher the molecular mechanisms allowing a host and a pathogen to adapt each other:
– the host attacking the pathogen (resistance) or defending and repairing itself (resilience)
– the pathogen hijacking the host defences or simply hiding itself, and sometimes attacking the host.
We work from both the host side (drosophila) and the pathogen side (bacteria and fungi).

Research projects

We are mainly focused on the epithelial barrier of the intestine, in infection models using Gram-negative bacteria (Serratia marcescens and Pseudomonas aeruginosa). We also study systemic effects with a parasitic infection model (the microsporidium Tubulinosema ratisbonensis).

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The Ferrandon group

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We are a very motivated small group, working all together in a helpful and enthusiastic atmosphere.

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Our publications

Haller, et al. EMBO Reports 2018

Lee et al., Cell Host & Microbe 2016

Limmer et al., PNAS 2011

Cronin et al., Science 2009

Gottar et al., Cell 2006

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