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2014

Articles de journaux

21.

Goto, Akira; Fukuyama, Hidehiro ; Imler, Jean-Luc ; Hoffmann, Jules A

The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response Article de journal

The Journal of Biological Chemistry, 289 (30), p. 20470–20476, 2014, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Cell Line, Chromatin Assembly and Disassembly, Epistasis, Escherichia coli, Escherichia coli Infections, Genetic, Immunity, Innate, NF-kappa B, Repressor Proteins, Signal Transduction, Transcription Factors

2013

Articles de journaux

20.

Fukuyama, Hidehiro; Verdier, Yann; Guan, Yongsheng; Makino-Okamura, Chieko; Shilova, Victoria; Liu, Xi; Maksoud, Elie; Matsubayashi, Jun; Haddad, Iman; Spirohn, Kerstin; Ono, Kenichiro; Hetru, Charles; Rossier, Jean; Ideker, Trey; Boutros, Michael; Vinh, Joëlle; Hoffmann, Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Article de journal

Proc. Natl. Acad. Sci. U.S.A., 110 (26), p. 10717–10722, 2013, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, Host-Pathogen Interactions, Humans, IMD interactome, Insect, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier

19.

Kobayashi, Taira; Ogawa, Michinaga; Sanada, Takahito; Mimuro, Hitomi; Kim, Minsoo; Ashida, Hiroshi; Akakura, Reiko; Yoshida, Mitsutaka; Kawalec, Magdalena; Reichhart, Jean-Marc; Mizushima, Tsunehiro; Sasakawa, Chihiro

The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection Article de journal

Cell Host Microbe, 13 (5), p. 570–583, 2013, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Animal, Bacillary, Bacterial, Bacterial Proteins, Caspases, Cell Death, Cell Line, Disease Models, DNA, Dysentery, Enzyme Inhibitors, Epithelial Cells, Escherichia coli, Gene Knockout Techniques, Guinea Pigs, Host-Pathogen Interactions, Humans, Initiator, Protein Binding, Protein Interaction Mapping, Salmonella typhimurium, Sequence Analysis, Shigella flexneri, Virulence Factors

18.

Baron, Olga Lucia; van West, Pieter; Industri, Benoit; Ponchet, Michel; Dubreuil, Géraldine; Gourbal, Benjamin; Reichhart, Jean-Marc; Coustau, Christine

Parental transfer of the antimicrobial protein LBP/BPI protects Biomphalaria glabrata eggs against oomycete infections Article de journal

PLoS Pathog., 9 (12), p. e1003792, 2013, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Antimicrobial Cationic Peptides, Biomphalaria, Blood Proteins, Carrier Proteins, Cell Membrane, Cell Membrane Permeability, Cloning, Escherichia coli, Female, Immunity, Infection, Maternally-Acquired, Membrane Glycoproteins, Microbial Sensitivity Tests, Molecular, Oomycetes, Recombinant Proteins, Zygote

2009

Articles de journaux

17.

Shia, Alice K H; Glittenberg, Marcus; Thompson, Gavin; Weber, Alexander N R; Reichhart, Jean-Marc; Ligoxygakis, Petros

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes Article de journal

J. Cell. Sci., 122 (Pt 24), p. 4505–4515, 2009, ISSN: 1477-9137.

Résumé | Liens | BibTeX | Étiquettes: Enterococcus faecalis, Escherichia coli, Fat Body, Hemocytes, Larva, Toll-Like Receptors

2005

Articles de journaux

16.

Kocks, Christine; Cho, Ju Hyun ; Nehme, Nadine ; Ulvila, Johanna ; Pearson, Alan M; Meister, Marie ; Strom, Charles ; Conto, Stephanie L; Hetru, Charles ; Stuart, Lynda M; Stehle, Thilo ; Hoffmann, Jules A; Reichhart, Jean-Marc ; Ferrandon, Dominique ; Rämet, Mika ; Ezekowitz, Alan R B

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila Article de journal

Cell, 123 (2), p. 335–346, 2005, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Amino Acid Motifs, Bacterial Infections, Cell Surface, Embryo, Escherichia coli, Flow Cytometry, Frameshift Mutation, Genes, Histidine, In Situ Hybridization, Insect, Insect Proteins, Macrophages, Membrane Proteins, Messenger, Nonmammalian, Open Reading Frames, Phagocytosis, Receptors, RNA, RNA Interference, Sequence Homology, Serratia marcescens

15.

Irving, Phil; Ubeda, Jean-Michel; Doucet, Daniel; Troxler, Laurent; Lagueux, Marie; Zachary, Daniel; Hoffmann, Jules A; Hetru, Charles; Meister, Marie

New insights into Drosophila larval haemocyte functions through genome-wide analysis Article de journal

Cell. Microbiol., 7 (3), p. 335–350, 2005, ISSN: 1462-5814.

Résumé | Liens | BibTeX | Étiquettes: bioinformatic, Catechol Oxidase, Cell Lineage, Enzyme Precursors, Escherichia coli, Fat Body, Gene Expression Profiling, Genome, Hemocytes, Integrin alpha Chains, Integrins, Larva, Micrococcus luteus

2002

Articles de journaux

14.

Ligoxygakis, Petros; Pelte, Nadège ; Hoffmann, Jules A; Reichhart, Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Article de journal

Science, 297 (5578), p. 114–116, 2002, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, Hypocreales, Insect, Insect Proteins, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, Serine Endopeptidases, Tertiary, Toll-Like Receptors

13.

Tauszig-Delamasure, Servane; Bilak, Hana ; Capovilla, Maria ; Hoffmann, Jules A; Imler, Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Article de journal

Nature Immunology, 3 (1), p. 91–97, 2002, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Amino Acid, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, Hypocreales, Immunologic, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2000

Articles de journaux

12.

Hetru, Charles; Letellier, L; Oren, Z; Hoffmann, Jules A; Shai, Y

Androctonin, a hydrophilic disulphide-bridged non-haemolytic anti-microbial peptide: a plausible mode of action Article de journal

Biochem. J., 345 Pt 3 , p. 653–664, 2000, ISSN: 0264-6021.

Résumé | BibTeX | Étiquettes: Adenosine Triphosphate, Anti-Bacterial Agents, Cations, Cell Membrane Permeability, Cytoplasm, Disulfides, Electron, Escherichia coli, Fluoresceins, Fluorescent Dyes, Fourier Transform Infrared, Gram-Negative Bacteria, Insect Proteins, Liposomes, Microbial Sensitivity Tests, Micrococcus luteus, Microscopy, Oxygen, Phospholipids, Potassium, Proteins, Spectroscopy

1999

Articles de journaux

11.

Levashina, Elena A; Langley, E; Green, C; Gubb, David ; Ashburner, M; Hoffmann, Jules A; Reichhart, Jean-Marc

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila Article de journal

Science, 285 (5435), p. 1917–1919, 1999, ISSN: 0036-8075.

Résumé | BibTeX | Étiquettes: Antifungal Agents, Antimicrobial Cationic Peptides, Body Patterning, Cell Surface, Escherichia coli, Genes, Hemolymph, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Mutagenesis, Peptides, Receptors, Recombinant Fusion Proteins, Serine Proteinase Inhibitors, Serpins, Signal Transduction, Toll-Like Receptors, Up-Regulation

10.

Lamberty, M; Ades, S; Uttenweiler-Joseph, S; Brookhart, G; Bushey, D; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Article de journal

J. Biol. Chem., 274 (14), p. 9320–9326, 1999, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, Insect Proteins, Larva, Lepidoptera, Micrococcus luteus, Proteins, Sequence Homology

9.

Lowenberger, C A; Kamal, S; Chiles, J; Paskewitz, S; Bulet, Philippe; Hoffmann, Jules A; Christensen, B M

Mosquito-Plasmodium interactions in response to immune activation of the vector Article de journal

Exp. Parasitol., 91 (1), p. 59–69, 1999, ISSN: 0014-4894.

Résumé | Liens | BibTeX | Étiquettes: Aedes, Anopheles, Culicidae, Defensins, Digestive System, Escherichia coli, Female, Genetic, Hemolymph, Insect Vectors, Messenger, Micrococcus luteus, Plasmodium, Plasmodium berghei, Plasmodium gallinaceum, Proteins, Reverse Transcriptase Polymerase Chain Reaction, RNA, Transcription

1998

Articles de journaux

8.

Braun, A; Hoffmann, Jules A; Meister, Marie

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes Article de journal

Proc. Natl. Acad. Sci. U.S.A., 95 (24), p. 14337–14342, 1998, ISSN: 0027-8424.

Résumé | BibTeX | Étiquettes: Adipose Tissue, Candida, Escherichia coli, Fungal, Genotype, Hemocytes, Larva, Melanins, Micrococcus luteus, Spores

1996

Articles de journaux

7.

Richman, A M; Bulet, Philippe; Hetru, Charles; Barillas-Mury, Carolina; Hoffmann, Jules A; Kafalos, Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Article de journal

Insect Mol. Biol., 5 (3), p. 203–210, 1996, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Amino Acid, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, Insect, Insect Vectors, Larva, Micrococcus luteus, Molecular, Sequence Homology

6.

Lowenberger, C A; Ferdig, M T; Bulet, Philippe; Khalili, S; Hoffmann, Jules A; Christensen, B M

Aedes aegypti: induced antibacterial proteins reduce the establishment and development of Brugia malayi Article de journal

Exp. Parasitol., 83 (2), p. 191–201, 1996, ISSN: 0014-4894.

Résumé | Liens | BibTeX | Étiquettes: Aedes, Analysis of Variance, Anti-Bacterial Agents, Base Sequence, Blood Proteins, Blotting, Brugia malayi, Culicidae, Defensins, DNA, Escherichia coli, Fat Body, Genetic, Gerbillinae, Micrococcus luteus, Microfilaria, Northern, RNA, Transcription

1995

Articles de journaux

5.

Lowenberger, C; Bulet, Philippe; Charlet, Maurice; Hetru, Charles; Hodgeman, B; Christensen, B M; Hoffmann, Jules A

Insect immunity: isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti Article de journal

Insect Biochem. Mol. Biol., 25 (7), p. 867–873, 1995, ISSN: 0965-1748.

Résumé | BibTeX | Étiquettes: Aedes, Amino Acid, Anti-Bacterial Agents, Blood Proteins, Defensins, Escherichia coli, Gram-Negative Bacteria, Gram-Positive Bacteria, Immunity, Insect Vectors, Micrococcus luteus, Sequence Homology, Stereoisomerism

4.

Bulet, Philippe; Hegy, G; Lambert, J; van Dorsselaer, Alan; Hoffmann, Jules A; Hetru, Charles

Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity Article de journal

Biochemistry, 34 (22), p. 7394–7400, 1995, ISSN: 0006-2960.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Carbohydrate Sequence, Carbohydrates, Diptera, Escherichia coli, Glycopeptides, Hemolymph, Insect Hormones, Insect Proteins, Larva, Mass Spectrometry, Plants, Trisaccharides

1993

Articles de journaux

3.

Bulet, Philippe; Dimarcq, Jean-Luc; Hetru, Charles; Lagueux, Marie; Charlet, Maurice; Hegy, G; Dorsselaer, Alan Van; Hoffmann, Jules A

A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution Article de journal

J. Biol. Chem., 268 (20), p. 14893–14897, 1993, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Carbohydrates, Cloning, DNA, Escherichia coli, Gas Chromatography-Mass Spectrometry, Glycopeptides, Glycosylation, Molecular

1990

Articles de journaux

2.

Wicker, C; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Hultmark, D; Samakovlis, C; Hoffmann, Jules A

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides Article de journal

J. Biol. Chem., 265 (36), p. 22493–22498, 1990, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Cloning, Diptera, DNA, Escherichia coli, Insect Hormones, Insect Proteins, Molecular, Multigene Family, Nucleic Acid, Oligonucleotide Probes, Sequence Homology

1988

Articles de journaux

1.

Dimarcq, Jean-Luc; Keppi, E; Dunbar, B; Lambert, J; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Rankine, S M; Fothergill, J E; Hoffmann, Jules A

Insect immunity. Purification and characterization of a family of novel inducible antibacterial proteins from immunized larvae of the dipteran Phormia terranovae and complete amino-acid sequence of the predominant member, diptericin A Article de journal

Eur. J. Biochem., 171 (1-2), p. 17–22, 1988, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Amino Acids, Anti-Bacterial Agents, Diptera, Escherichia coli, Insect Hormones, Insect Proteins, Isoelectric Point, Larva