Tout voire

2013

Articles de journaux

27.

Fukuyama, Hidehiro; Verdier, Yann; Guan, Yongsheng; Makino-Okamura, Chieko; Shilova, Victoria; Liu, Xi; Maksoud, Elie; Matsubayashi, Jun; Haddad, Iman; Spirohn, Kerstin; Ono, Kenichiro; Hetru, Charles; Rossier, Jean; Ideker, Trey; Boutros, Michael; Vinh, Joëlle; Hoffmann, Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Article de journal

Proc. Natl. Acad. Sci. U.S.A., 110 (26), p. 10717–10722, 2013, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, Host-Pathogen Interactions, Humans, IMD interactome, Insect, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier

2012

Articles de journaux

26.

Liu, Xi; Sano, Teruyuki; Guan, Yongsheng; Nagata, Shigekazu; Hoffmann, Jules A; Fukuyama, Hidehiro

Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif Article de journal

PLoS ONE, 7 (8), p. e42725, 2012, ISSN: 1932-6203.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Blotting, Conserved Sequence, Endodeoxyribonucleases, Eye Proteins, Immunoprecipitation, Phosphoprotein Phosphatases, Sequence Homology, Transcription Factors, Western

2010

Articles de journaux

25.

Garcia, Alvaro Baeza; Pierce, Raymond J; Gourbal, Benjamin; Werkmeister, Elisabeth; Colinet, Dominique; Reichhart, Jean-Marc; Dissous, Colette; Coustau, Christine

Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni Article de journal

PLoS Pathog., 6 (9), p. e1001115, 2010, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Apoptosis, Biomphalaria, Blotting, Cell Proliferation, Cells, Cricetinae, Cultured, Hemocytes, Host-Parasite Interactions, Humans, Liver, Macrophage Migration-Inhibitory Factors, Messenger, Oocysts, Recombinant Proteins, Reverse Transcriptase Polymerase Chain Reaction, RNA, Schistosoma mansoni, Schistosomiasis mansoni, Sequence Homology, Small Interfering, Western

2008

Articles de journaux

24.

Deddouche, Safia; Matt, Nicolas ; Budd, Aidan ; Mueller, Stefanie ; Kemp, Cordula ; Galiana-Arnoux, Delphine ; Dostert, Catherine ; Antoniewski, Christophe ; Hoffmann, Jules A; Imler, Jean-Luc

The DExD/Ħ-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila Article de journal

Nature Immunology, 9 (12), p. 1425–1432, 2008, ISSN: 1529-2916.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Electrophoresis, Fat Body, Gene Expression Regulation, Genetic, Genetically Modified, Humans, Phylogeny, Polyacrylamide Gel, Reverse Transcriptase Polymerase Chain Reaction, Ribonuclease III, RNA Helicases, Sequence Homology, Transcription, Virus Diseases

2005

Articles de journaux

23.

Kocks, Christine; Cho, Ju Hyun ; Nehme, Nadine ; Ulvila, Johanna ; Pearson, Alan M; Meister, Marie ; Strom, Charles ; Conto, Stephanie L; Hetru, Charles ; Stuart, Lynda M; Stehle, Thilo ; Hoffmann, Jules A; Reichhart, Jean-Marc ; Ferrandon, Dominique ; Rämet, Mika ; Ezekowitz, Alan R B

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila Article de journal

Cell, 123 (2), p. 335–346, 2005, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Amino Acid Motifs, Bacterial Infections, Cell Surface, Embryo, Escherichia coli, Flow Cytometry, Frameshift Mutation, Genes, Histidine, In Situ Hybridization, Insect, Insect Proteins, Macrophages, Membrane Proteins, Messenger, Nonmammalian, Open Reading Frames, Phagocytosis, Receptors, RNA, RNA Interference, Sequence Homology, Serratia marcescens

22.

Weber, Alexander N R; Moncrieffe, Martin C; Gangloff, Monique; Imler, Jean-Luc; Gay, Nicholas J

Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway Article de journal

The Journal of Biological Chemistry, 280 (24), p. 22793–22799, 2005, ISSN: 0021-9258.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Biophysical Phenomena, Biophysics, Body Patterning, Calorimetry, Cell Line, Cell Surface, Cross-Linking Reagents, Cytokines, Dimerization, Electrophoresis, Humans, Ligands, Luciferases, Membrane Glycoproteins, Polyacrylamide Gel, Protein Binding, Protein Structure, Receptors, Recombinant Proteins, Sequence Homology, Signal Transduction, Tertiary, Time Factors, Toll-Like Receptors, Ultracentrifugation

2002

Articles de journaux

21.

Tauszig-Delamasure, Servane; Bilak, Hana ; Capovilla, Maria ; Hoffmann, Jules A; Imler, Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Article de journal

Nature Immunology, 3 (1), p. 91–97, 2002, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Amino Acid, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, Hypocreales, Immunologic, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2001

Articles de journaux

20.

Michel, T; Reichhart, Jean-Marc ; Hoffmann, Jules A; Royet, Julien

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Article de journal

Nature, 414 (6865), p. 756–759, 2001, ISSN: 0028-0836.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Anti-Bacterial Agents, Anti-Infective Agents, Bacillus thuringiensis, Carrier Proteins, Cell Surface, Chromosome Mapping, Enterococcus faecalis, Fungi, Genes, Gram-Positive Bacteria, Hemolymph, Humans, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Mutation, Receptors, Sequence Homology, Toll-Like Receptors

19.

Lamberty, M; Zachary, Daniel; Lanot, R; Bordereau, C; Robert, A; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Constitutive expression of a cysteine-rich antifungal and a linear antibacterial peptide in a termite insect. Article de journal

J. Biol. Chem., 276 (6), p. 4085–4092, 2001, ISSN: 0021-9258.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Anti-Bacterial Agents, Antifungal Agents, Base Sequence, Chromatography, Cysteine, DNA Primers, High Pressure Liquid, Immunohistochemistry, Isoptera, Peptides, Protein Conformation, Recombinant Proteins, Sequence Homology

2000

Articles de journaux

18.

Lagueux, Marie; Perrodou, E; Levashina, Elena A; Capovilla, Maria; Hoffmann, Jules A

Constitutive expression of a complement-like protein in toll and JAK gain-of-function mutants of Drosophila Article de journal

Proc. Natl. Acad. Sci. U.S.A., 97 (21), p. 11427–11432, 2000, ISSN: 0027-8424.

Résumé | Liens | BibTeX | Étiquettes: alpha-Macroglobulins, Amino Acid, Cell Surface, Complement C3, Esters, Genetic, Insect Proteins, Janus Kinases, Membrane Glycoproteins, Mutation, Protein-Tyrosine Kinases, Proteins, Receptors, Sequence Homology, Sulfhydryl Compounds, Toll-Like Receptors, Transcription, Transcription Factors

17.

Tauszig, Servane; Jouanguy, Emmanuelle ; Hoffmann, Jules A; Imler, Jean-Luc

Toll-related receptors and the control of antimicrobial peptide expression in Drosophila Article de journal

Proceedings of the National Academy of Sciences of the United States of America, 97 (19), p. 10520–10525, 2000, ISSN: 0027-8424.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Anti-Bacterial Agents, Blotting, Cell Line, Cell Surface, Membrane Glycoproteins, Multigene Family, Northern, Peptides, Receptors, Reverse Transcriptase Polymerase Chain Reaction, Sequence Homology, Toll-Like Receptor 2, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptors

1999

Articles de journaux

16.

Lamberty, M; Ades, S; Uttenweiler-Joseph, S; Brookhart, G; Bushey, D; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Article de journal

J. Biol. Chem., 274 (14), p. 9320–9326, 1999, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, Insect Proteins, Larva, Lepidoptera, Micrococcus luteus, Proteins, Sequence Homology

15.

Lowenberger, C A; Smartt, C T; Bulet, Philippe; Ferdig, M T; Severson, D W; Hoffmann, Jules A; Christensen, B M

Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti Article de journal

Insect Mol. Biol., 8 (1), p. 107–118, 1999, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Aedes, Amino Acid, Base Sequence, Blotting, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Hemolymph, Molecular, Northern, Protein Isoforms, Proteins, Sequence Homology

1998

Articles de journaux

14.

Taguchi, S; Bulet, Philippe; Hoffmann, Jules A

A novel insect defensin from the ant Formica rufa Article de journal

Biochimie, 80 (4), p. 343–346, 1998, ISSN: 0300-9084.

Résumé | BibTeX | Étiquettes: Amino Acid, Anti-Bacterial Agents, Ants, Chromatography, High Pressure Liquid, Insect Proteins, Insects, Mass, Matrix-Assisted Laser Desorption-Ionization, Protein Structure, Secondary, Sequence Alignment, Sequence Homology, Spectrometry

1996

Articles de journaux

13.

Barillas-Mury, Carolina; Charlesworth, A; Gross, I; Richman, A; Hoffmann, Jules A; Kafatos, Fotis C

Immune factor Gambif1, a new rel family member from the human malaria vector, Anopheles gambiae Article de journal

EMBO J., 15 (17), p. 4691–4701, 1996, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Amino Acid, Anopheles, Base Sequence, Biological Transport, Cell Nucleus, Cells, Complementary, Cultured, DNA, DNA-Binding Proteins, Insect Proteins, Insect Vectors, NF-kappa B, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-rel, Sequence Homology, Trans-Activators, Transcriptional Activation

12.

Charlet, Maurice; Chernysh, S; Philippe, H; Hetru, Charles; Hoffmann, Jules A; Bulet, Philippe

Innate immunity. Isolation of several cysteine-rich antimicrobial peptides from the blood of a mollusc, Mytilus edulis Article de journal

J. Biol. Chem., 271 (36), p. 21808–21813, 1996, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Anti-Infective Agents, Antifungal Agents, Bivalvia, Blood Proteins, Chromatography, Cysteine, Defensins, High Pressure Liquid, Molecular Weight, Phylogeny, Sequence Homology

11.

Richman, A M; Bulet, Philippe; Hetru, Charles; Barillas-Mury, Carolina; Hoffmann, Jules A; Kafalos, Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Article de journal

Insect Mol. Biol., 5 (3), p. 203–210, 1996, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Amino Acid, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, Insect, Insect Vectors, Larva, Micrococcus luteus, Molecular, Sequence Homology

10.

Fehlbaum, P; Bulet, Philippe; Chernysh, S; Briand, J P; Roussel, J P; Letellier, L; Hetru, Charles; Hoffmann, Jules A

Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides Article de journal

Proc. Natl. Acad. Sci. U.S.A., 93 (3), p. 1221–1225, 1996, ISSN: 0027-8424.

Résumé | BibTeX | Étiquettes: Amino Acid, Amphibian Proteins, Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Cyclic, Fungi, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, Mass Spectrometry, Microbial Sensitivity Tests, Peptides, Ranidae, Sequence Homology, Skin, Structure-Activity Relationship

1995

Articles de journaux

9.

Lowenberger, C; Bulet, Philippe; Charlet, Maurice; Hetru, Charles; Hodgeman, B; Christensen, B M; Hoffmann, Jules A

Insect immunity: isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti Article de journal

Insect Biochem. Mol. Biol., 25 (7), p. 867–873, 1995, ISSN: 0965-1748.

Résumé | BibTeX | Étiquettes: Aedes, Amino Acid, Anti-Bacterial Agents, Blood Proteins, Defensins, Escherichia coli, Gram-Negative Bacteria, Gram-Positive Bacteria, Immunity, Insect Vectors, Micrococcus luteus, Sequence Homology, Stereoisomerism

8.

Cornet, B; Bonmatin, J M; Hetru, Charles; Hoffmann, Jules A; Ptak, M; Vovelle, F

Refined three-dimensional solution structure of insect defensin A Article de journal

Structure, 3 (5), p. 435–448, 1995, ISSN: 0969-2126.

Résumé | BibTeX | Étiquettes: Amino Acid, Bacteriolysis, Chemistry, Defensins, Diptera, Gram-Positive Bacteria, Hydrogen Bonding, Insect Hormones, Magnetic Resonance Spectroscopy, Models, Molecular, Physical, Physicochemical Phenomena, Protein Conformation, Recombinant Proteins, Sequence Homology, Solutions, Structure-Activity Relationship

1994

Articles de journaux

7.

Fehlbaum, P; Bulet, Philippe; Michaut, L; Lagueux, Marie; Broekaert, W F; Hetru, Charles; Hoffmann, Jules A

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Article de journal

J. Biol. Chem., 269 (52), p. 33159–33163, 1994, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Antifungal Agents, Base Sequence, Cloning, Complementary, DNA, Insect Proteins, Male, Messenger, Microbial Sensitivity Tests, Molecular, Peptide Biosynthesis, Peptides, Plants, Protein Biosynthesis, Protein Precursors, Proteins, RNA, Sequence Homology

6.

Cociancich, S; Dupont, A; Hegy, G; Lanot, R; Holder, F; Hetru, Charles; Hoffmann, Jules A; Bulet, Philippe

Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus Article de journal

Biochem. J., 300 ( Pt 2) , p. 567–575, 1994, ISSN: 0264-6021.

Résumé | BibTeX | Étiquettes: Amino Acid, Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Proteins, Chromatography, Defensins, Gas Chromatography-Mass Spectrometry, Gel, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, Hemolymph, Insect Proteins, Peptides, Sequence Homology

1993

Articles de journaux

5.

Hoffmann, Jules A; Hetru, Charles ; Reichhart, Jean-Marc

The humoral antibacterial response of Drosophila Article de journal

FEBS Lett., 325 (1-2), p. 63–66, 1993, ISSN: 0014-5793.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Genes, Insect, Insect Hormones, Insect Proteins, Sequence Homology

1992

Articles de journaux

4.

Hoffmann, Jules A; Hetru, Charles

Insect defensins: inducible antibacterial peptides Article de journal

Immunol. Today, 13 (10), p. 411–415, 1992, ISSN: 0167-5699.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Bacterial Infections, Blood Bactericidal Activity, Blood Proteins, Defensins, Insects, Peptides, Sequence Homology

1990

Articles de journaux

3.

Hoffmann, Jules A; Hoffmann, Danièle

The inducible antibacterial peptides of dipteran insects Article de journal

Res. Immunol., 141 (9), p. 910–918, 1990, ISSN: 0923-2494.

BibTeX | Étiquettes: Antimicrobial Cationic Peptides, Defensins, Diptera, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, Nucleic Acid, Proteins, Sequence Homology, Transcription

2.

Lagueux, Marie; Lwoff, L; Meister, Marie; Goltzené, F; Hoffmann, Jules A

cDNAs from neurosecretory cells of brains of Locusta migratoria (Insecta, Orthoptera) encoding a novel member of the superfamily of insulins Article de journal

Eur. J. Biochem., 187 (1), p. 249–254, 1990, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Base Sequence, DNA, Genes, Grasshoppers, Humans, Insulin, Multigene Family, Nervous System, Neuropeptides, Neurosecretory Systems, Nucleic Acid, Nucleic Acid Hybridization, Oligonucleotide Probes, RNA, Sequence Homology

1.

Wicker, C; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Hultmark, D; Samakovlis, C; Hoffmann, Jules A

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides Article de journal

J. Biol. Chem., 265 (36), p. 22493–22498, 1990, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Cloning, Diptera, DNA, Escherichia coli, Insect Hormones, Insect Proteins, Molecular, Multigene Family, Nucleic Acid, Oligonucleotide Probes, Sequence Homology