Tout voire

2014

Articles de journaux

31.

Majzoub, Karim; Hafirassou, Mohamed Lamine ; Meignin, Carine ; Goto, Akira ; Marzi, Stefano ; Fedorova, Antonina ; Verdier, Yann ; Vinh, Joëlle ; Hoffmann, Jules A; Martin, Franck ; Baumert, Thomas F; Schuster, Catherine ; Imler, Jean-Luc

RACK1 controls IRES-mediated translation of viruses Article de journal

Cell, 159 (5), p. 1086–1095, 2014, ISSN: 1097-4172.

Résumé | Liens | BibTeX | Étiquettes: Cell Line, Cell Surface, Cytoplasmic and Nuclear, Dicistroviridae, GTP-Binding Proteins, Hepacivirus, Hepatocytes, Humans, Insect Viruses, Models, Molecular, Neoplasm Proteins, Peptide Initiation Factors, Protein Biosynthesis, Receptors, Regulatory Sequences, Ribonucleic Acid, Tumor, Virus Replication

30.

Imler, Jean-Luc

Overview of Drosophila immunity: a historical perspective Article de journal

Developmental and Comparative Immunology, 42 (1), p. 3–15, 2014, ISSN: 1879-0089.

Résumé | Liens | BibTeX | Étiquettes: Allergy and Immunology, Animal, Antimicrobial Cationic Peptides, Antimicrobial peptides, History, Humans, IMD pathway, Immunity, Innate, innate immunity, Models, Pattern recognition receptors, Signal Transduction, Toll-Like Receptors

2013

Articles de journaux

29.

Fukuyama, Hidehiro; Verdier, Yann; Guan, Yongsheng; Makino-Okamura, Chieko; Shilova, Victoria; Liu, Xi; Maksoud, Elie; Matsubayashi, Jun; Haddad, Iman; Spirohn, Kerstin; Ono, Kenichiro; Hetru, Charles; Rossier, Jean; Ideker, Trey; Boutros, Michael; Vinh, Joëlle; Hoffmann, Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Article de journal

Proc. Natl. Acad. Sci. U.S.A., 110 (26), p. 10717–10722, 2013, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, Host-Pathogen Interactions, Humans, IMD interactome, Insect, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier

2011

Articles de journaux

28.

Imler, Jean-Luc; Ferrandon, Dominique

[Innate immunity crowned 2011 Nobel Prize winner] Article de journal

Med Sci (Paris), 27 , p. 1019–24, 2011, ISSN: 0767-0974 (Print) 0767-0974 (Linking).

Liens | BibTeX | Étiquettes: *Immunity, *Nobel Prize, Biological, Genetic Association Studies, Humans, Immunotherapy/methods/trends, Innate/genetics, Models, Molecular Targeted Therapy/trends, Seasons, Structure-Activity Relationship, Toll-Like Receptors/chemistry/genetics/isolation & purification/physiology

27.

Ogawa, Michinaga; Yoshikawa, Yuko; Kobayashi, Taira; Mimuro, Hitomi; Fukumatsu, Makoto; Kiga, Kotaro; Piao, Zhenzi; Ashida, Hiroshi; Yoshida, Mitsutaka; Kakuta, Shigeru; Koyama, Tomohiro; Goto, Yoshiyuki; Nagatake, Takahiro; Nagai, Shinya; Kiyono, Hiroshi; Kawalec, Magdalena; Reichhart, Jean-Marc; Sasakawa, Chihiro

A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens Article de journal

Cell Host Microbe, 9 (5), p. 376–389, 2011, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Autophagy, Biological, Cells, Cultured, Membrane Proteins, Mice, Microtubule-Associated Proteins, Models, Phagosomes, Protein Interaction Mapping, Shigella, Two-Hybrid System Techniques

26.

Lee, Kwang-Zin; Ferrandon, Dominique

Negative regulation of immune responses on the fly Article de journal

EMBO J., 30 (6), p. 988–990, 2011, ISSN: 1460-2075.

Liens | BibTeX | Étiquettes: *Gene Expression Regulation, *Homeostasis, Bacteria, Bacteria/*immunology, Biological, Drosophila melanogaster/*immunology, Drosophila Proteins/biosynthesis/metabolism, Gene Expression Regulation, Homeostasis, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinases/metabolism, Models, NF-kappa B, NF-kappa B/metabolism, ras Proteins, ras Proteins/metabolism, Receptor Protein-Tyrosine Kinases, Receptor Protein-Tyrosine Kinases/metabolism

2010

Articles de journaux

25.

Silverman, Gary A; Whisstock, James C; Bottomley, Stephen P; Huntington, James A; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Bird, Phillip I

Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems Article de journal

J. Biol. Chem., 285 (32), p. 24299–24305, 2010, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Biological, Caenorhabditis elegans, Cell Death, Cell Differentiation, Cell Survival, Homeostasis, Humans, Immunity, Innate, Mice, Models, Phenotype, Serpins, Transgenes, Transgenic

24.

Whisstock, James C; Silverman, Gary A; Bird, Phillip I; Bottomley, Stephen P; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Huntington, James A

Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions Article de journal

J. Biol. Chem., 285 (32), p. 24307–24312, 2010, ISSN: 1083-351X.

Résumé | Liens | BibTeX | Étiquettes: Biological, Biological Transport, Biophysics, Catalytic Domain, Hormones, Humans, Kinetics, Models, Peptide Hydrolases, Protein Binding, Protein Conformation, Protein Structure, Serpins, Substrate Specificity, Tertiary, Thrombin

23.

Paquette, Nicholas; Broemer, Meike; Aggarwal, Kamna; Chen, Li; Husson, Marie; Ertürk-Hasdemir, Deniz; Reichhart, Jean-Marc; Meier, Pascal; Silverman, Neal

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling Article de journal

Mol. Cell, 37 (2), p. 172–182, 2010, ISSN: 1097-4164.

Résumé | Liens | BibTeX | Étiquettes: Alleles, Amino Acid Motifs, Biological, Caspases, Inhibitor of Apoptosis Proteins, MAP Kinase Kinase Kinases, Models, NF-kappa B, Sequence Alignment, Signal Transduction, Ubiquitin-Protein Ligases, Ubiquitination

2009

Articles de journaux

22.

Fraiture, Malou; Baxter, Richard H G; Steinert, Stefanie; Chelliah, Yogarany; Frolet, Cécile; Quispe-Tintaya, Wilber; Hoffmann, Jules A; Blandin, Stéphanie A; Levashina, Elena A

Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium Article de journal

Cell Host Microbe, 5 (3), p. 273–284, 2009, ISSN: 1934-6069.

Résumé | Liens | BibTeX | Étiquettes: Anopheles, APL1, Biological, Complement System Proteins, Hemolymph, Immunologic Factors, LRIM1, Models, Plasmodium, Protein Binding, Proteins, TEP1

21.

Cronin, Shane J F; Nehme, Nadine T; Limmer, Stefanie; Liegeois, Samuel; Pospisilik, Andrew J; Schramek, Daniel; Leibbrandt, Andreas; de Simoes, Ricardo Matos; Gruber, Susanne; Puc, Urszula; Ebersberger, Ingo; Zoranovic, Tamara; Neely, Gregory G; von Haeseler, Arndt; Ferrandon, Dominique; Penninger, Josef M

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection Article de journal

Science, 325 (5938), p. 340–343, 2009, ISSN: 1095-9203.

Résumé | Liens | BibTeX | Étiquettes: *Genome, *RNA Interference, Animal, Cell Proliferation, Drosophila melanogaster/*genetics/immunology/*microbiology, Drosophila Proteins/genetics/metabolism, Epithelial Cells, Epithelial Cells/cytology/physiology, Genetically Modified, Genome, Hemocytes, Hemocytes/immunology/metabolism/microbiology, Homeostasis, Immunity, Innate, Innate/*genetics, Insect, Intestinal Mucosa, Intestinal Mucosa/cytology/immunology/metabolism/microbiology, Janus Kinases, Janus Kinases/genetics/metabolism, Models, RNA Interference, Serratia Infections, Serratia Infections/genetics/*immunology/microbiology, Serratia marcescens, Serratia marcescens/*immunology/physiology, Signal Transduction, STAT Transcription Factors, STAT Transcription Factors/genetics/metabolism, Stem Cells, Stem Cells/cytology/physiology

2007

Articles de journaux

20.

Ferrandon, Dominique

Ubiquitin-proteasome: pallbearer carries the deceased to the grave Article de journal

Immunity, 27 (4), p. 541–544, 2007, ISSN: 1074-7613.

Résumé | Liens | BibTeX | Étiquettes: *Models, Apoptosis, Apoptosis/*physiology, Immunological, Macrophages, Macrophages/immunology/metabolism, Models, Phagocytosis, Phagocytosis/*physiology, Proteasome Endopeptidase Complex, Proteasome Endopeptidase Complex/*metabolism, Ubiquitin, Ubiquitin/*metabolism

19.

Ferrandon, Dominique; Gottar, Marie; Gobert, Vanessa

[New mechanism for detection of infections using the innate immune system of animals] Article de journal

Med Sci (Paris), 23 (8-9), p. 707–709, 2007, ISSN: 0767-0974.

Liens | BibTeX | Étiquettes: Animal, Drosophila/immunology, Gram-Positive Bacteria, Gram-Positive Bacteria/pathogenicity, Gram-Positive Bacterial Infections, Gram-Positive Bacterial Infections/immunology, Humans, Immune System, Infection, Infection/*diagnosis/*immunology, Models

2006

Articles de journaux

18.

Gottar, Marie; Gobert, Vanessa ; Matskevich, Alexey A; Reichhart, Jean-Marc ; Wang, Chengshu ; Butt, Tariq M; Belvin, Marcia ; Hoffmann, Jules A; Ferrandon, Dominique

Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors Article de journal

Cell, 127 (7), p. 1425–1437, 2006, ISSN: 0092-8674.

Résumé | Liens | BibTeX | Étiquettes: Antibody Formation, Beauveria, Candida albicans, Carrier Proteins, Cellular, Glucans, Immunity, Immunological, Metarhizium, Models, Polysaccharides, Serine Endopeptidases, Signal Transduction, Virulence Factors

17.

Chen, Li-Ying; Wang, Juinn-Chin; Hyvert, Yann; Lin, Hui-Ping; Perrimon, Norbert; Imler, Jean-Luc; Hsu, Jui-Chou

Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo Article de journal

Current biology: CB, 16 (12), p. 1183–1193, 2006, ISSN: 0960-9822.

Résumé | Liens | BibTeX | Étiquettes: Adaptor Proteins, Antigens, Biological, Body Patterning, Cell Membrane, Differentiation, Dimerization, DNA-Binding Proteins, Embryo, Epistasis, Genetic, Immunity, Immunologic, Innate, Models, Mutation, Nonmammalian, Phenotype, Phosphoproteins, Receptors, Signal Transducing, Toll-Like Receptors, Transcription Factors, Zinc Fingers

2005

Articles de journaux

16.

Martinelli, Cosimo; Reichhart, Jean-Marc

Evolution and integration of innate immune systems from fruit flies to man: lessons and questions Article de journal

J. Endotoxin Res., 11 (4), p. 243–248, 2005, ISSN: 0968-0519.

Résumé | Liens | BibTeX | Étiquettes: Biological Evolution, Cell Surface, Forecasting, Humans, Immunity, Immunological, Innate, Membrane Glycoproteins, Models, Receptors, Signal Transduction, Toll-Like Receptor 5, Toll-Like Receptors

2004

Articles de journaux

15.

Leclerc, Vincent; Reichhart, Jean-Marc

The immune response of Drosophila melanogaster Article de journal

Immunol. Rev., 198 , p. 59–71, 2004, ISSN: 0105-2896.

Résumé | BibTeX | Étiquettes: Cell Surface, Immunity, Immunological, Innate, Models, Receptors, Signal Transduction, Toll-Like Receptors

14.

Ferrandon, Dominique; Imler, Jean-Luc; Hoffmann, Jules A

Sensing infection in Drosophila: Toll and beyond Article de journal

Semin Immunol, 16 , p. 43–53, 2004, ISSN: 1044-5323.

Résumé | BibTeX | Étiquettes: Carrier Proteins/chemistry/immunology/physiology, Cell Surface/immunology/*physiology, Drosophila Proteins/chemistry/immunology/*physiology, Drosophila/genetics/*immunology/microbiology, Fungi/immunology, Gene Expression Regulation, Gram-Negative Bacterial Infections/immunology, Gram-Positive Bacterial Infections/immunology, Immunological, Insect Proteins/chemistry/immunology/physiology, Models, Non-U.S. Gov't, Receptors, Signal Transduction/immunology/physiology, Support

13.

Blandin, Stephanie; Shiao, Shin-Hong; Moita, Luis F; Janse, Chris J; Waters, Andrew P; Kafatos, Fotis C; Levashina, Elena A

Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae Article de journal

Cell, 116 (5), p. 661–670, 2004, ISSN: 0092-8674.

Résumé | BibTeX | Étiquettes: Anopheles, Female, Genetic, Humans, Insect Proteins, Insect Vectors, Malaria, Models, Molecular, Plasmodium berghei, Polymorphism, Protein Structure, RNA, Sequence Alignment, Tertiary

2003

Articles de journaux

12.

Imler, Jean-Luc; Hoffmann, Jules A

Toll signaling: the TIReless quest for specificity Article de journal

Nature Immunology, 4 (2), p. 105–106, 2003, ISSN: 1529-2908.

Liens | BibTeX | Étiquettes: Cell Surface, Dendritic Cells, Humans, Immunological, Interferon-beta, Membrane Glycoproteins, Mice, Models, Protein Structure, Receptors, Signal Transduction, Tertiary, Toll-Like Receptors

11.

Luna, C; Hoa, N T; Zhang, J; Kanzok, S M; Brown, S E; Imler, Jean-Luc; Knudson, D L; Zheng, L

Characterization of three Toll-like genes from mosquito Aedes aegypti Article de journal

Insect Molecular Biology, 12 (1), p. 67–74, 2003, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Aedes, Base Sequence, Cell Surface, Chimera, Cloning, Developmental, Female, Gene Expression Regulation, Genetic, Insect Proteins, Male, Messenger, Models, Molecular, Mutagenesis, Promoter Regions, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sequence Alignment, Signal Transduction, Site-Directed, Transfection

2002

Articles de journaux

10.

Hoffmann, Jules A; Reichhart, Jean-Marc

Drosophila innate immunity: an evolutionary perspective Article de journal

Nat. Immunol., 3 (2), p. 121–126, 2002, ISSN: 1529-2908.

Résumé | Liens | BibTeX | Étiquettes: Biological Evolution, Cell Surface, Immunity, Immunological, Innate, Membrane Glycoproteins, Models, Receptors, Signal Transduction, Toll-Like Receptors

2000

Articles de journaux

9.

Imler, Jean-Luc; Tauszig, Servane ; Jouanguy, Emmanuelle ; Forestier, C; Hoffmann, Jules A

LPS-induced immune response in Drosophila Article de journal

Journal of Endotoxin Research, 6 (6), p. 459–462, 2000, ISSN: 0968-0519.

Résumé | BibTeX | Étiquettes: Biological, Cell Line, Cell Surface, Defensins, Genes, Genetic, Insect, Insect Proteins, Lipopolysaccharides, Membrane Glycoproteins, Models, Mutation, Promoter Regions, Receptors, Signal Transduction, Toll-Like Receptors

1999

Articles de journaux

8.

Hoffmann, Jules A; Kafatos, Fotis C; Janeway, Charles A; Ezekowitz, Alan R B

Phylogenetic perspectives in innate immunity Article de journal

Science, 284 (5418), p. 1313–1318, 1999, ISSN: 0036-8075.

Résumé | BibTeX | Étiquettes: Active, Culicidae, Humans, Immunity, Immunological, Infection, Innate, Insect Vectors, Mammals, Models, Phagocytosis, Phylogeny, Proteins

1997

Articles de journaux

7.

Meister, Marie; Lemaitre, Bruno; Hoffmann, Jules A

Antimicrobial peptide defense in Drosophila Article de journal

Bioessays, 19 (11), p. 1019–1026, 1997, ISSN: 0265-9247.

Résumé | Liens | BibTeX | Étiquettes: Anti-Infective Agents, Gene Expression Regulation, Genetic, Insect Proteins, Models, Peptides, Promoter Regions, Signal Transduction

6.

Ferrandon, Dominique; Koch, I; Westhof, Eric; Nüsslein-Volhard, C

RNA-RNA interaction is required for the formation of specific bicoid mRNA 3' UTR-STAUFEN ribonucleoprotein particles Article de journal

EMBO J., 16 (7), p. 1751–1758, 1997, ISSN: 0261-4189.

Résumé | Liens | BibTeX | Étiquettes: Base Sequence, Dimerization, DNA Primers, Embryo, Homeodomain Proteins, Insect Proteins, Messenger, Models, Nonmammalian, Nucleic Acid Conformation, Protein Biosynthesis, Ribonucleoproteins, RNA, RNA-Binding Proteins, Structural, Trans-Activators

1996

Articles de journaux

5.

Hoffmann, Jules A; Reichhart, Jean-Marc ; Hetru, Charles

Innate immunity in higher insects Article de journal

Curr. Opin. Immunol., 8 (1), p. 8–13, 1996, ISSN: 0952-7915.

Résumé | BibTeX | Étiquettes: Base Sequence, Cyclic, Immunity, Immunologic, Immunological, Innate, Insects, Models, Peptide Hydrolases, Peptides, Receptors

1995

Articles de journaux

4.

Cornet, B; Bonmatin, J M; Hetru, Charles; Hoffmann, Jules A; Ptak, M; Vovelle, F

Refined three-dimensional solution structure of insect defensin A Article de journal

Structure, 3 (5), p. 435–448, 1995, ISSN: 0969-2126.

Résumé | BibTeX | Étiquettes: Amino Acid, Bacteriolysis, Chemistry, Defensins, Diptera, Gram-Positive Bacteria, Hydrogen Bonding, Insect Hormones, Magnetic Resonance Spectroscopy, Models, Molecular, Physical, Physicochemical Phenomena, Protein Conformation, Recombinant Proteins, Sequence Homology, Solutions, Structure-Activity Relationship

1994

Articles de journaux

3.

Meister, Marie; Braun, A; Kappler, Christine ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter Article de journal

EMBO J., 13 (24), p. 5958–5966, 1994, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Anti-Infective Agents, Base Sequence, beta-Galactosidase, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic, Genetically Modified, Germ Cells, Insect Hormones, Insect Proteins, Male, Models, Nucleic Acid, Promoter Regions, Recombinant Fusion Proteins, Repetitive Sequences, Transformation

1992

Articles de journaux

2.

Bonmatin, J M; Bonnat, J L; Gallet, X; Vovelle, F; Ptak, M; Reichhart, Jean-Marc ; Hoffmann, Jules A; Keppi, E; Legrain, M; Achstetter, T

Two-dimensional 1H NMR study of recombinant insect defensin A in water: resonance assignments, secondary structure and global folding Article de journal

J. Biomol. NMR, 2 (3), p. 235–256, 1992, ISSN: 0925-2738.

Résumé | BibTeX | Étiquettes: Defensins, Hydrogen, Insect Hormones, Insects, Magnetic Resonance Spectroscopy, Models, Molecular, Protein Conformation, Recombinant Proteins, Saccharomyces cerevisiae, Thermodynamics

1988

Articles de journaux

1.

Kappler, Christine; Kabbouh, M; Hetru, Charles; Durst, F; Hoffmann, Jules A

Characterization of three hydroxylases involved in the final steps of biosynthesis of the steroid hormone ecdysone in Locusta migratoria (Insecta, Orthoptera) Article de journal

J. Steroid Biochem., 31 (6), p. 891–898, 1988, ISSN: 0022-4731.

Résumé | BibTeX | Étiquettes: Biological, Ecdysone, Grasshoppers, Kinetics, Mixed Function Oxygenases, Models, NAD, NADP, Subcellular Fractions